The lead ship of her class of four heavy cruisers for the Italian navy, Zara was launched on 27 April 1930. Commissioned into the Regia Marina on 20 October 1931, she took an active part in naval operations in the Mediterranean along with her sisters Fiume, Pola and Gorizia.
During the Battle of Cape Matapan, Zara and Fiume were sent to protect Pola which had been hit by an aerial torpedo. During the night, the three cruisers were surprized by a force of three British battleships (HMS Warspite, Valiant and Barham). All three heavy cruisers were lost.